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Table 2 Comparison between diagnostic characteristics of patients with and without late gadolinium enhancement (LGE)

From: Late gadolinium enhancement cardiovascular magnetic resonance predicts clinical worsening in patients with pulmonary hypertension

CMR

All patients (n = 58)

Patients with LGE (n = 40)

Patients without LGE (n = 18)

p value

Right ventricular end-diastolic volume index (ml/m2)

128 ± 57

137 ± 55

101 ± 55

0.03

Right ventricular end-systolic volume index (ml/m2)

84 ± 56

94 ± 53

57 ± 55

0.03

Right ventricular ejection fraction (%)

38 ± 15

35 ± 13

48 ± 14

< 0.01

Right ventricular mass index (g/m2)

27 ± 13

31 ± 13

19 ± 12

< 0.01

Right ventricular stroke volume (ml)

81 ± 26

81 ± 27

80 ± 22

0.98

Right atrial volume (ml)

133 ± 59

139 ± 59

112 ± 49

0.10

Right ventricular stroke work (mmHg × ml)

3776 ± 1766

3410 ± 2192

1934 ± 1581

0.02

Left ventricular end-diastolic volume index (ml/m2)

72 ± 27

72 ± 30

76 ± 21

0.51

Left ventricular end-systolic volume index (ml/m2)

32 ± 21

33 ± 22

33 ± 21

0.94

Left ventricular ejection fraction (%)

57 ± 10

56 ± 9.5

59 ± 11

0.34

Left ventricular mass index (g/m2)

41 ± 15

43 ± 17

37 ± 12

0.11

Left atrial volume (ml)

70 ± 33

65 ± 32

83 ± 33

0.06

Naughton-Balke Exercise Treadmill Test

All patients* (n = 42)

Patients with LGE (n = 30)

Patients without LGE (n = 12)

p value

Metabolic equivalents

5.6 ± 2.3

5.3 ± 2.3

6.5 ± 2.4

0.15

Right Heart Catheterization

All patients* (n = 35)

Patients with LGE (n = 27)

Patients without LGE (n = 8)

p value

Mean right atrial pressure (mmHg)

9.8 ± 5.0

10 ± 5.2

7 ± 3.0

0.08

Mean pulmonary artery pressure (mmHg)

49 ± 16

52 ± 16

35 ± 5.8

< 0.01

Pulmonary capillary wedge pressure (mmHg)

12 ± 5.4

12 ± 6.0

13 ± 3.1

0.68

Cardiac index (L/min/m2)

2.6 ± 0.99

2.4 ± 0.85

3.4 ± 1.3

0.08

Pulmonary vascular resistance (Wood Units)

9.5 ± 5.3

10 ± 5.7

5.2 ± 1.1

< 0.01

Mixed venous oxygen saturation (%)

62 ± 15

63 ± 11

66 ± 10

0.52

N-Terminal Pro Brain Natriuretic Peptide

All patients* (n = 43)

Patients with LGE (n = 30)

Patients without LGE (n = 13)

p value

NT-proBNP level (pg/mL)

2100 ± 4862

2334 ± 5316

705 ± 1330

0.13

  1. * Only hemodynamics, METS, and NT-proBNP testing within 4 months of the CMR study were included in analysis.
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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