55-year-old man healthy control. Time curves of circumferential strain (C-strain) on an anteroseptal segment as control. The x-axis indicates time frames (20 frame/cycle), and the y-axis indicates the C-strain value (%). Dotted line indicates the end-systolic frame. In normal contraction, peak C-strain was a negative value. The time curve of subendocardial C-strain shows a great peak at end-systole and epicardial C-strain is relatively small. ■: subendocardial C-strain, ○: epicardial C-strain.