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Table 1 Major risk factors for the assessment of sudden cardiac death in hypertrophic cardiomyopathy* (adapted from [7])

From: The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance

Major risk factors

Possible risk factors in individual patients

Cardiac arrest/ventricular fibrillation or spontaneously occurring and sustained VT

Atrial fibrillation

Family history of premature HCM-related sudden death

Left ventricular outflow obstruction

Left ventricular thickness equal to or greater than 30 mm, especially in adolescents and young adults

Intense physical exertion

Abnormal upright exercise blood pressure response that is attenuated or hypertensive (of greater predictive value in patients less than 50 yrs old or if hypotensive)

High risk gene mutation

Nonsustained ventricular tachycardia by Holter examination

 

Unexplained syncope, especially in young patients or when recurrent or exertional

 
  1. *risk factor assessed by imaging.