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Table 1 Major risk factors for the assessment of sudden cardiac death in hypertrophic cardiomyopathy* (adapted from [7])

From: The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance

Major risk factors Possible risk factors in individual patients
Cardiac arrest/ventricular fibrillation or spontaneously occurring and sustained VT Atrial fibrillation
Family history of premature HCM-related sudden death Left ventricular outflow obstruction
Left ventricular thickness equal to or greater than 30 mm, especially in adolescents and young adults Intense physical exertion
Abnormal upright exercise blood pressure response that is attenuated or hypertensive (of greater predictive value in patients less than 50 yrs old or if hypotensive) High risk gene mutation
Nonsustained ventricular tachycardia by Holter examination  
Unexplained syncope, especially in young patients or when recurrent or exertional  
  1. *risk factor assessed by imaging.