From: The diagnosis of hypertrophic cardiomyopathy by cardiovascular magnetic resonance
Study | Number of patients | % of study population with LGE | Event Rate Positive LGE versus Negative LGE groups | Hazard ratio (HR) or relative risk (RR) | Primary endpoint |
---|---|---|---|---|---|
O'Hanlon et al. 2010 [73]. | 217 | 63 | 24.5% LGE+ vs. 9.9% LGE- had primary endpoint | HR 3.4 [1.4-8.1] | Cardiovascular death, unplanned cardiovascular admission, sustained ventricular tachycardia or ventricular fibrillation, appropriate implantable cardioverter-defibrillator discharge |
Rubinshtein et al. 2010[111]. | 424 | 56 | 3.3% of LGE+ patients had SCD/ICD | n/a | Sudden cardiac death and appropriate implanted cardioverter defibrillator (ICD) discharge |
Bruder et al. 2010 [118] | 220 | 67.2 | 94% LGE+ vs. 66% LGE- had primary endpoint | HR 8.0 [1.0-61.9] | Sudden cardiac death and appropriate implanted cardioverter defibrillator (ICD) discharge. |
Adabag et al. 2008 [70] | 177 | 40.6 | 28% LGE+ vs. 4% LGE- w/NSVT | RR 7.3 [2.6-20.4] | Nonsustained ventricular tachycardia (NSVT) by Holter monitor |
Paya et al. 2008 [113] | 120 | 69 | 38% LGE+ vs. 8% LGE- had NSVT (p < 0.05) | not indicated | Nonsustained ventricular tachycardia (NSVT) by Holter monitor |
Suk et al. 2008 [119] | 25 | 64 | 88% LGE+ vs. 53% LGE- had VT (p < 0.05) | not indicated | Ventricular tachycardia by Holter or resting ECG |