Table 1 Animal characteristic and left ventricular performance
BSN | Day 3 | Day 10 | Day 30 | Day 60 | Day 90 | p-value | |
|---|---|---|---|---|---|---|---|
LVEF (%) | 52.7 ± 1.3 | 47.0 ± 2.4 | 43.3 ± 2.2 | 41.2 ± 2.0 | 38.1 ± 2.9 | 39.1 ± 2.8 | <0.001 |
LVSV (ml) | 21.0 ± 0.9 | 16.0 ± 0.8 | 16.8 ± 0.8 | 16.3 ± 1.1 | 17.6 ± 2.0 | 19.2 ± 1.9 | 0.03 |
LVEDV (ml) | 40.3 ± 2.5 | 36.0 ± 2.5 | 39.2 ± 1.9 | 39.8 ± 2.6 | 46.3 ± 3.6 | 49.4 ± 3.5 | 0.002 |
LVESV (ml) | 19.3 ± 1.7 | 19.8 ± 2.1 | 22.4 ± 1.7 | 23.5 ± 2.0 | 28.7 ± 2.7 | 30.2 ± 2.7 | <0.001 |
LVED mass (gram) | 32.1 ± 1.5 | 34.7 ± 1.7 | 34.4 ± 2.4 | 32.3 ± 1.6 | 35.8 ± 1.6 | 38.6 ± 1.8 | 0.01 |
BW (kg) | 30.8 ± 1.5 | 29.7 ± 1.4 | 32.0 ± 1.8 | 31.7 ± 1.0 | 33.9 ± 1.2 | 35.1 ± 1.7 | 0.1 |