Table 1 Baseline Characteristics

Age (yrs)

66.4±8.8

70.8±5.9

64.5±9.2

0.001

CAD risk factors

Diabetes

16 (24%)

5 (25%)

11 (23%)

0.85

Hypertension

45 (66%)

16 (80%)

29 (60%)

0.12

Cigarette smoking

21 (30%)

5 (25%)

16 (33%)

0.50

Hyperlipidemia

41 (60%)

18 (90%)

23 (48%)

0.001

Family history of CAD

33 (49%)

9 (45%)

24 (50%)

0.71

Menopause

66 (97%)

20 (100%)

46 (96%)

0.35

Obesity (BMI ≥ 30 kg/m ² )

19 (28%)

6 (30%)

13 (27%)

0.81

Number of risk factors

3.5±1.4

4.0±1.2

3.4±1.5

0.13

Rose chest pain questionnaire

Angina

41 (61%)

13 (68%)

28 (58%)

0.45

Medications

Statins

20 (29%)

8 (40%)

12 (25%)

0.22

Beta-blockers

35 (51%)

14 (70%)

21 (44%)

0.05

Aspirin

43 (63%)

15 (75%)

28 (58%)

0.19

ACE-inhibitors

27 (40%)

8 (40%)

19 (40%)

0.97

Nitrates

7 (10%)

2 (10%)

5 (10%)

1.00††

Diuretics

19 (28%)

3 (15%)

16 (33%)

0.12

Hormone replacement†

32 (48%)

8 (40%)

24 (52%)

0.41

Blood tests ‡

Fasting glucose (mg/dL)

99.3±16.6

101.7±15.6

98.4±17.1

0.52

Lipids

Total cholesterol (mg/dL)

225.3±36.8

237.6±33.8

220.2±37.2

0.08

LDL (mg/dL)

137.0±32.5

147.3±28.5

132.7±33.4

0.09

HDL (mg/dL)

59.8±16.8

59.9±19.6

59.7±15.6

0.97

Triglycerides (mg/dL)

146.7±70.0

152.3±71.1

144.4±70.2

0.68

hs-CRP (mg/dL)

0.36±0.5

0.48±0.7

0.32±0.4

0.35

Indication for angiography

Positive stress nuclear study

9 (13%)

5 (25%)

4 (8%)

Positive stress echo study

6 (9%)

3 (15%)

3 (6%)

Positive treadmill ECG study

39 (57%)

9 (45%)

30 (63%)

Clinical symptoms alone

14 (21%)

3 (15%)

11 (23%)

12-lead ECG

Q-wave ||

5 (7%)

1 (5%)

4 (8%)

1.00††

RBBB #

2 (3%)

1 (5%)

1 (2%)

1.00††