Table 2 Demographics, RHC, Echocardiography and CMR Data
No PH n = 39 | PH n = 194 | |
|---|---|---|
Demographics | ||
Age (yrs) | 61 ± 16 | 63 ± 15 |
Female (%) | 56% | 59% |
WHO class I | 3 (1.5%) | |
II | 42 (21.6%) | |
III | 127 (65.5%) | |
IV | 22 (11.3%) | |
Invasive catheter measurements | ||
mRAP (mmHg) | 6 ± 3 | 11 ± 5† |
mPAP (mmHg) | 19 ± 3 | 45 ± 12† |
PCWP (mmHg) | 11 ± 5 | 12 ± 6 |
CO (L.min) | 7.0 ± 1.8 | 5.1 ± 1.7† |
CI (L.min.m-2) | 3.7 ± 0.7 | 2.9 ± 0.9† |
PVR (dyn.s.cm-5) | 149 ± 167 | 587 ± 411† |
Mixed VO2 (%) | 73.5 ± 6.3 | 63.8 ± 9.2† |
Echocardiography (n = 195) | ||
TRJV (cm/s) | 2.6 ± 0.6 | 3.9 ± 0.9† |
Echo derived mPAP (mmHg) | 25.4 ± 7.6 | 46.8 ± 16.6† |
MR – RV morphology | ||
RVEDVI (ml/m2) | 77.7 ± 24.6 | 99.1 ± 39.0† |
RV mass index (g/m2) | 13.7 ± 6.92 | 37.6 ± 18.7† |
VMI (ratio) | 0.26 ± 0.11 | 0.70 ± 0.35† |
Late gadolinium enhancement, ratio and % (n = 159) | 2/31 (6%) | 108/128 (86%) |
MR – RV function | ||
RVEF (%) | 39.7 ± 14.5 | 28.2 ± 14.5† |
RVSVI (ml/m2) | 31.4 ± 13.3 | 23.3 ± 13.2† |
TAPSE (cm) | 2.21 ± 0.66 | 1.55 ± 0.76† |
f-TAAD (%) | 24.6 ± 7.89 | 15.9 ± 7.49† |
SFD (cm) | 1.10 ± 0.45 | 0.64 ± 0.52† |
f-SFD (%) | 27.1 ± 11.5 | 14.4 ± 12.3† |
RVRAC (%) | 39.8 ± 10.5 | 26.2 ± 13.4† |
sEI (ratio) | 1.19 ± 0.19 | 1.57 ± 0.52† |
dEI (ratio) | 1.17 ± 0.12 | 1.28 ± 0.23 |
Phase contrast – Pulmonary artery (n = 106) | ||
Average velocity (cm/s) | 13.6 ± 6.7 | 7.6 ± 3.4† |
Retrograde flow (L/min/m2) | 0.2 ± 0.1 | 0.5 ± 0.3† |
Retrograde flow (%) | 9.3 ± 7.2 | 16.3 ± 9.2† |
PA relative area change ≥ 15% | 17.8 ± 6.6 | 8.1 ± 6.5† |
Systolic PA area (cm2) | 7.8 ± 4.6 | 9.7 ± 2.8† |
Diastolic PA area (cm2) | 6.7 ± 4.7 | 8.9 ± 2.8† |