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Table 5 Sensitivity, Specificity, Positive and Negative Predictive Values and area under the receiver operating characteristic curve (AUC) of CMR Indices for the Detection of PH

From: Diagnostic accuracy of cardiovascular magnetic resonance imaging of right ventricular morphology and function in the assessment of suspected pulmonary hypertension results from the ASPIRE registry

  Sensitivity Specificity PPV NPV AUC
Cardiac morphology
RVEDV index ≥ 75 ml/m2 67 50 89 20 0.72*
RV mass index ≥ 20 g/m2 83 84 96 50 0.91*
VMI ≥ 0.4 81 88 97 50 0.91*
Late gadolinium enhancement 83 94 98 58 0.89*
Right heart functional indices
RVEF ≤ 35% 67 71 93 28 0.72*
RVSVI ≤ 30 ml/m2 70 47 89 21 0.68*
TAPSE ≤ 2 cm 76 64 92 32 0.75*
f-TAAD ≤ 25% 88 56 92 44 0.78*
SFD ≤ 1 cm 77 67 93 34 0.73*
f-SFD ≤ 25% 79 64 92 35 0.78*
RVRAC ≤ 30% 61 81 95 28 0.79*
sEI ≥ 1.2 65 61 90 24 0.72*
dEI ≥ 1.17 62 54 88 20 0.57
Phase contrast CMR
Average velocity ≤ 10 (cm/s) 82 62 94 32 0.80*
Retrograde flow ≥ 0.3 (L/min/m2) 83 71 95 38 0.84*
Retrograde flow (%) 73 56 87 34 0.75*
PA relative area change ≥ 15% 86 70 94 48 0.87*
Systolic PA area ≥ 8 cm2 74 67 92 32 0.77*
Diastolic PA area ≥ 6 cm2 88 66 94 52 0.82*
  1. AUC (area under the curve) *p < 0.05.