Figure 1

Flow chart showing the steps in image co-registration. The cardiac atlas labels are co-registered to the baseline cine and LGE sequences to segment the myocardium. The infarct itself is then segmented using a Gaussian mixture model. The baseline and follow-up cine images are first rigidly aligned for anatomical consistency. A non-rigid registration is then used to build a map of local ventricular dilatation by tracking the relative position of intrinsic landmarks shared by the images.