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Table 2 Segmental and global inter-study reproducibility for five different feature tracking strain parameters and the study sample size required to detect an absolute change of 5% with 90% power and an α error of 0.05

From: Inter-study reproducibility of cardiovascular magnetic resonance myocardial feature tracking

  Mean difference ± SD Coefficient of Variation ICC (95%CI) Sample size
Segmental     
ErrSAX −3.5 ± 7.5% 35.9% 0.57 (0.35-0.71) 48
EccSAX 1.2 ± 6.5% 38.0% 0.68 (0.55-0.78) 36
ErrLAX 1.5 ± 9.2% 53.2% 0.62 (0.47-0.73) 72
EllLV −1.0 ± 11.3 55.4% 0.59 (0.44-0.71) 108
EllRV −1.9 ± 13.6 60.0% 0.56 (0.41-0.69) 156
Global     
ErrSAX −3.2 ± 5.7% 27.2% 0.61 (0.15-0.85) 28
EccSAX 1.0 ± 3.5% 20.3% 0.70 (0.32-0.89) 11
ErrLAX 1.5 ± 5.8% 33.3% 0.44 (0–0.77) 29
EllLV −1.08 ± 5.4% 26.4% 0.44 (0–0.77) 25
EllRV −1.9 ± 6.8% 29.9% 0.62 (0.20-0.85) 39
  1. SD = Standard deviation; ICC = Intraclass correlation coefficient; CI = Confidence Interval
  2. Sample size numbers must be doubled for studies comparing active treatment vs. placebo.