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Table 1 Characteristics of patients with different forms of remodeling and hypertrophy

From: Left ventricular remodeling and hypertrophy in patients with aortic stenosis: insights from cardiovascular magnetic resonance

  Normal ventricle Concentric remodeling Asymmetric remodeling Concentric hypertrophy Asymmetric hypertrophy LV decompensation P value
Number 11 11 11 34 14 10 -
Male sex (%) 45 55 82 65 64 60 0.62
Age (years) 52 ± 26 54 ± 21 70 ± 12 57 ± 18 75 ± 11 69 ± 18 0.01*
CMR DATA
Indexed LVEDV (mL/m2) 76 ± 9 55 ± 12 56 ± 9 77 ± 19 78 ± 24 126 ± 34 <0.01*
LV mass index (g/m2) 63 ± 11 75 ± 10 78 ± 7 113 ± 21 110 ± 24 106 ± 18 <0.01*
M/V (g/mL) 0.84 ± 0.16 1.39 ± 0.31 1.43 ± 0.28 1.51 ± 0.28 1.47 ± 0.33 0.88 ± 0.19 <0.01*
Maximal wall thickness (mm) 11 ± 2 13 ± 3 17 ± 2 15 ± 2 17 ± 2 13 ± 2 <0.01*
Ejection Fraction (%) 73 ± 5 77 ± 9 76 ± 15 70 ± 13 67 ± 14 45 ± 16 <0.01*
Impaired Ejection Fraction (%) 0 0 0 15 14 100 <0.01*
Aortic valve area (cm2) 0.85 ± 0.30 0.90 ± 0.43 1.10 ± 0.32 0.98 ± 0.34 0.86 ± 0.25 0.80 ± 0.16 0.22
Peak Velocity (m/s) 3.6 ± 0.4 3.6 ± 0.8 3.42 ± 0.67 4.0 ± 0.97 3.80 ± 0.76 3.8 ± 0.8 0.17
Severe AS (%) 73 64 45 65 78 100 0.13
CLINICAL DATA
Bicuspid valve (%) 55 45 27 41 29 40 0.76
Hypertension (%) 9 18 64 38 64 50 0.03*
Diabetes Mellitus (%) 18 0 18 15 7 30 0.45
ACEi/ARB (%) 20 10 55 39 36 22 0.18
Beta blocker (%) 20 10 37 18 18 20 0.56
  1. Demographic, CMR and clinical data for patients with normal LV structure, concentric remodeling, asymmetric remodeling, concentric hypertrophy, asymmetric hypertrophy and LV decompensation.