| Normal ventricle | Concentric remodeling | Asymmetric remodeling | Concentric hypertrophy | Asymmetric hypertrophy | LV decompensation | P value |
---|---|---|---|---|---|---|---|
Number | 11 | 11 | 11 | 34 | 14 | 10 | - |
Male sex (%) | 45 | 55 | 82 | 65 | 64 | 60 | 0.62 |
Age (years) | 52 ± 26 | 54 ± 21 | 70 ± 12 | 57 ± 18 | 75 ± 11 | 69 ± 18 | 0.01* |
CMR DATA | |||||||
Indexed LVEDV (mL/m2) | 76 ± 9 | 55 ± 12 | 56 ± 9 | 77 ± 19 | 78 ± 24 | 126 ± 34 | <0.01* |
LV mass index (g/m2) | 63 ± 11 | 75 ± 10 | 78 ± 7 | 113 ± 21 | 110 ± 24 | 106 ± 18 | <0.01* |
M/V (g/mL) | 0.84 ± 0.16 | 1.39 ± 0.31 | 1.43 ± 0.28 | 1.51 ± 0.28 | 1.47 ± 0.33 | 0.88 ± 0.19 | <0.01* |
Maximal wall thickness (mm) | 11 ± 2 | 13 ± 3 | 17 ± 2 | 15 ± 2 | 17 ± 2 | 13 ± 2 | <0.01* |
Ejection Fraction (%) | 73 ± 5 | 77 ± 9 | 76 ± 15 | 70 ± 13 | 67 ± 14 | 45 ± 16 | <0.01* |
Impaired Ejection Fraction (%) | 0 | 0 | 0 | 15 | 14 | 100 | <0.01* |
Aortic valve area (cm2) | 0.85 ± 0.30 | 0.90 ± 0.43 | 1.10 ± 0.32 | 0.98 ± 0.34 | 0.86 ± 0.25 | 0.80 ± 0.16 | 0.22 |
Peak Velocity (m/s) | 3.6 ± 0.4 | 3.6 ± 0.8 | 3.42 ± 0.67 | 4.0 ± 0.97 | 3.80 ± 0.76 | 3.8 ± 0.8 | 0.17 |
Severe AS (%) | 73 | 64 | 45 | 65 | 78 | 100 | 0.13 |
CLINICAL DATA | |||||||
Bicuspid valve (%) | 55 | 45 | 27 | 41 | 29 | 40 | 0.76 |
Hypertension (%) | 9 | 18 | 64 | 38 | 64 | 50 | 0.03* |
Diabetes Mellitus (%) | 18 | 0 | 18 | 15 | 7 | 30 | 0.45 |
ACEi/ARB (%) | 20 | 10 | 55 | 39 | 36 | 22 | 0.18 |
Beta blocker (%) | 20 | 10 | 37 | 18 | 18 | 20 | 0.56 |