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Table 1 Characteristics of patients with different forms of remodeling and hypertrophy

From: Left ventricular remodeling and hypertrophy in patients with aortic stenosis: insights from cardiovascular magnetic resonance

 

Normal ventricle

Concentric remodeling

Asymmetric remodeling

Concentric hypertrophy

Asymmetric hypertrophy

LV decompensation

P value

Number

11

11

11

34

14

10

-

Male sex (%)

45

55

82

65

64

60

0.62

Age (years)

52 ± 26

54 ± 21

70 ± 12

57 ± 18

75 ± 11

69 ± 18

0.01*

CMR DATA

Indexed LVEDV (mL/m2)

76 ± 9

55 ± 12

56 ± 9

77 ± 19

78 ± 24

126 ± 34

<0.01*

LV mass index (g/m2)

63 ± 11

75 ± 10

78 ± 7

113 ± 21

110 ± 24

106 ± 18

<0.01*

M/V (g/mL)

0.84 ± 0.16

1.39 ± 0.31

1.43 ± 0.28

1.51 ± 0.28

1.47 ± 0.33

0.88 ± 0.19

<0.01*

Maximal wall thickness (mm)

11 ± 2

13 ± 3

17 ± 2

15 ± 2

17 ± 2

13 ± 2

<0.01*

Ejection Fraction (%)

73 ± 5

77 ± 9

76 ± 15

70 ± 13

67 ± 14

45 ± 16

<0.01*

Impaired Ejection Fraction (%)

0

0

0

15

14

100

<0.01*

Aortic valve area (cm2)

0.85 ± 0.30

0.90 ± 0.43

1.10 ± 0.32

0.98 ± 0.34

0.86 ± 0.25

0.80 ± 0.16

0.22

Peak Velocity (m/s)

3.6 ± 0.4

3.6 ± 0.8

3.42 ± 0.67

4.0 ± 0.97

3.80 ± 0.76

3.8 ± 0.8

0.17

Severe AS (%)

73

64

45

65

78

100

0.13

CLINICAL DATA

Bicuspid valve (%)

55

45

27

41

29

40

0.76

Hypertension (%)

9

18

64

38

64

50

0.03*

Diabetes Mellitus (%)

18

0

18

15

7

30

0.45

ACEi/ARB (%)

20

10

55

39

36

22

0.18

Beta blocker (%)

20

10

37

18

18

20

0.56

  1. Demographic, CMR and clinical data for patients with normal LV structure, concentric remodeling, asymmetric remodeling, concentric hypertrophy, asymmetric hypertrophy and LV decompensation.