Inclusion criteria | Exclusion criteria |
---|---|
CCS Class 2 and 3AND EITHER: 2 or more of the following risk factors (diabetes, hypertension, smoking, family history, hypercholesterolaemia) OR Positive Exercise treadmill/bicycle test | Contra-indications to CMR |
 | Contra-indications to adenosine (AV-block2 or 3, symptomatic bradycardia, COPD with evidence of bronchospasm or asthma) |
 | Cardiac arrhythmias which may compromise image quality, atrial fibrillation or frequent ectopic beats > 20 bpm) |
Age > 18 yrs | Known Left ventricular ejection fraction of less than 30% |
Willing to undergo all study procedures | Persistent CCS class 4 angina |
 | NYHA class 3 and 4 |
 | Previous coronary artery bypass grafts |
 | PCI within the previous 6 months |
 | Poor renal function (GFR < 30 ml/min) and /or allergy to contrast media |
 | Inability to lie supine for 60 mins |
 | Unstable medically |
 | Participating in any other clinical trial |
 | Pregnancy / breast feeding |