Table 1 Clinical studies of CMR MO
From: CMR of microvascular obstruction and hemorrhage in myocardial infarction
Study | Method of MO assessment | Imaging time post-MI | Prevalence of MO | Findings |
|---|---|---|---|---|
Positive studies | ||||
Wu et al.[43] N = 44 | · Early (yes/no) | 10 days | 25% | MO predicted MACE at 16 mos. independently of infarct size |
Hombach et al.[20] N = 110 | · LGE (yes/no) | 6 days | 46% | Late MO predicted MACE at 7.5 mos., independently of LVEF, LVEDV, infarct size |
Bruder et al.[44] N = 67 | · EGE | 5 days | 61% | EGE MO > 0.5% predicted 1-yr MACE independently of LVEF & infarct size |
Cochet et al.[45] N = 184 | · First-pass LGE | 3-7 days | 69% (FP) | Late MO predicted 1-yr MACE independently of LVEF & infarct size |
47% (LGE) | ||||
De Waha et al.[46] N = 408 | · EGE LGE | 3 days | 81% (FP) | Late MO (presence/amount) better predicted MACE at 19 mos. with incremental value over LVEF & infarct size |
73% (LGE) | ||||
Negative studies | ||||
Bodi et al.[47] N = 214 | · LGE (yes/no) | 7 days | 31% | Infarct transmural extent & wall motion score independently predicted MACE at 1.5 years. |
Larose et al.[48] N = 103 | · First-pass | <12 h | Not reported | Infarct size was the strongest predictor of 6 mo. LVEF & 2-yr MACE |
|  |  | 6 months |  |  |