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Table 2 Relationships between carotid stenosis, intraplaque hemorrhage (IPH) presence and size, and sensitivity/specificity of the high intensity signal (HIS) on TOF-MRA MIP images for IPH classification

From: Quantitative evaluation of high intensity signal on MIP images of carotid atherosclerotic plaques from routine TOF-MRA reveals elevated volumes of intraplaque hemorrhage and lipid rich necrotic core

Stenosis

N (%)

% with IPH

Mean IPH

Sensitivity (95% CI)

Specificity

   

Volume (mm3)*

 

(95% CI)

0 – 15%

37 (48.7)

13.5

45.7

0.0 (0.0 – 52.2)

100.0 (89.1 – 100.0)

16 – 49%

21 (27.6)

42.9

52.2

22.2 (2.8 – 60.0)

100.0 (73.5 – 100.0)

50 – 99%

18 (23.7)

61.1

122.9

54.5 (23.3 – 83.3)

100.0 (59.0 – 100.0)

p for trend

-

< 0.001

0.030

0.022

1.000

  1. *In those with IPH present. Chi-squared test for trend. Spearman’s rank correlation. CI = confidence interval.