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Table 2 Relationships between carotid stenosis, intraplaque hemorrhage (IPH) presence and size, and sensitivity/specificity of the high intensity signal (HIS) on TOF-MRA MIP images for IPH classification

From: Quantitative evaluation of high intensity signal on MIP images of carotid atherosclerotic plaques from routine TOF-MRA reveals elevated volumes of intraplaque hemorrhage and lipid rich necrotic core

Stenosis N (%) % with IPH Mean IPH Sensitivity (95% CI) Specificity
    Volume (mm3)*   (95% CI)
0 – 15% 37 (48.7) 13.5 45.7 0.0 (0.0 – 52.2) 100.0 (89.1 – 100.0)
16 – 49% 21 (27.6) 42.9 52.2 22.2 (2.8 – 60.0) 100.0 (73.5 – 100.0)
50 – 99% 18 (23.7) 61.1 122.9 54.5 (23.3 – 83.3) 100.0 (59.0 – 100.0)
p for trend - < 0.001 0.030 0.022 1.000
  1. *In those with IPH present. Chi-squared test for trend. Spearman’s rank correlation. CI = confidence interval.