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Table 1

From: Different patterns of myocardial iron overload by T2* Cardiovascular MR as markers of risk for cardiac complication in thalassemia major

 

Homogeneous MIO (N=138)

Heterogeneous MIO and global Heart T2* < 20 ms (N=97)

Heterogeneous MIO and global Heart T2* ≥ 20 ms (N=238)

No MIO (N=339)

P-value

Sex (M/F)

67/71

38/59

119/119

157/172

0.304

Age (years)

28.9 ± 7.4

30.8 ± 7.4

30.4 ± 8.9

31.1 ± 8.9

0.069

Hb pre-transfusion (g/dl)

9.7 ± 0.6

9.6 ± 0.5

9.7 ± 0.6

9.6 ± 0.8

0.309

Ferritin levels (ng/l)

2454 ± 1969

2043 ± 1796

1328 ± 1277

1114 ± 1004

<0.0001

Cardiac disease, n (%)

34 (24.6%)

20 (20.6%)

20 (8.4%)

56 (16.5%)

<0.0001

Heart failure, n (%)

24 (17.4%)

16 (16.5%)

10 (4.2%)

28 (8.3%)

<0.0001

Arrhythmias, n (%)

13 (9.4%)

6 (6.2%)

8 (3.4%)

23 (6.8%)

0.112

Pulmonary hypertension, n (%)

3 (2.2%)

1 (1.0%)

4 (1.7%)

14 (4.1%)

0.192