Table 1 Patient characteristics
All patients | High EPA group | Low EPA group | *P value | |
|---|---|---|---|---|
(n = 127) | (n = 64) | (n = 63) | ||
Age | 71.6 ± 7.8 | 71.8 ± 7.6 | 70.1 ± 9.1 | 0.18 |
Male | 116 (91%) | 60 (94%) | 56 (89%) | 0.12 |
Height, cm | 163.4 ± 7.1 | 162.9 ± 7.7 | 164.4 ± 6.5 | 0.29 |
Body weight, kg | 65.4 ± 11.1 | 65.9 ± 11.7 | 64.3 ± 9.7 | 0.51 |
Body mass index, kg/m2 | 24.3 ± 3.0 | 24.6 ± 3.2 | 23.7 ± 2.5 | 0.69 |
Systolic BP, mmHg | 137.9 ± 20.8 | 135.7 ± 19.2 | 140.5 ± 22.3 | 0.24 |
Diastolic BP, mmHg | 70.7 ± 12.6 | 69.6 ± 13.3 | 71.8 ± 11.9 | 0.35 |
Heart rate, beats per minute | 67.9 ± 12.4 | 66.3 ± 10.7 | 69.6 ± 13.8 | 0.18 |
Cardiovascular history | ||||
Myocardial infarction | 42 (33%) | 19 (30%) | 23 (37%) | 0.64 |
Angina pectoris | 64 (50%) | 35 (55%) | 29 (46%) | 0.22 |
Coronary risk factors | ||||
Hypertension | 93 (73%) | 47 (73%) | 46 (73%) | 0.88 |
Dyslipidemia | 92 (72%) | 46 (72%) | 46 (73%) | 0.84 |
Diabetes Mellitus | 39 (31%) | 20 (31%) | 19 (30%) | 0.89 |
Current smoking | 16 (13%) | 9 (14%) | 7 (11%) | 0.48 |
Family history of CAD | 6 (5%) | 3 (5%) | 3 (5%) | 0.92 |
Obesity | 41 (32%) | 25 (39%) | 16 (25%) | 0.13 |
Blood test results | ||||
EPA, μg/mL | 85.3 ± 53.9 | 121.5 ± 53.3 | 48.4 ± 16.9 | <0.001 |
DHA, μg/mL | 139.1 ± 54.4 | 163.2 ± 51.9 | 109.0 ± 35.2 | <0.001 |
AA, μg/mL | 178.6 ± 52.9 | 171.0 ± 47.3 | 179.6 ± 52.5 | 0.34 |
Total cholesterol, mmol/L | 179.0 ± 38.6 | 183.1 ± 36.7 | 172.8 ± 37.9 | 0.12 |
LDL cholesterol, mmol/L | 101.9 ± 26.7 | 106.6 ± 31.7 | 100.2 ± 27.5 | 0.23 |
HDL cholesterol, mmol/L | 57.3 ± 15.9 | 66.1 ± 64.0 | 53.0 ± 14.3 | 0.12 |
Triglyceride, mmol/L | 179.0 ± 38.6 | 171.1 ± 125.1 | 157.6 ± 105.6 | 0.51 |
Hemoglobin, g/dL | 14.3 ± 1.6 | 14.3 ± 1.4 | 14.1 ± 1.6 | 0.58 |
HbA1c, % | 6.0 ± 0.9 | 6.0 ± 1.0 | 5.8 ± 0.8 | 0.21 |
eGFR, mL/min/1.73 m2 | 65.7 ± 14.0 | 64.5 ± 13.2 | 65.6 ± 13.6 | 0.65 |
CRP, mg/dL | 0.30 ± 1.0 | 0.15 ± 0.21 | 0.42 ± 1.37 | 0.25 |
BNP, pg/dl | 53.3 ± 65.0 | 46.6 ± 43.9 | 45.9 ± 63.2 | 0.94 |
Medication use | ||||
Statin | 82 (65%) | 41 (64%) | 41 (65%) | 0.86 |
Antiplatelet agent | 108 (85%) | 52 (81%) | 56 (89%) | 0.91 |
Calcium channel blocker | 45 (35%) | 22 (34%) | 23 (37%) | 0.99 |
β blocker | 48 (38%) | 21 (33%) | 27 (43%) | 0.26 |
ACE/ARB | 73 (57%) | 33 (52%) | 40 (63%) | 0.17 |