Relationship between coronary flow reserve evaluated by phase-contrast cine cardiovascular magnetic resonance and serum eicosapentaenoic acid

Table 3 Coronary sinus blood flow at rest and during ATP infusion in groups with low and high EPA

	All patients, (N = 127)	High EPA group, (n = 64)	Low EPA group, (n = 63)	* P-value
HR at rest, bpm	68 ± 12	66 ± 11	70 ± 14	0.14
HR during ATP infusion, bpm	71 ± 12	69 ± 11	73 ± 12	0.086
SBP at rest, mmHg	138 ± 21	136 ± 19	140 ± 22	0.22
SBP during ATP infusion, mmHg	117 ± 20**	117 ± 19**	117 ± 22**	1.00
DBP at rest, mmHg	71 ± 13	69 ± 13	72 ± 12	0.33
DBP during ATP infusion, mmHg	62 ± 12**	62 ± 13**	72 ± 12**	0.87
RPP at rest	9432 ± 2505	9047 ± 2206	9825 ± 2739	0.11
RPP during ATP infusion	8303 ± 2105**	8116 ± 2111**	8508 ± 2100**	0.34
cCS flow at rest (mL/min)	77.4 ± 32.7	82.3 ± 35.0	79.1 ± 32.4	0.59
cCS flow during ATP infusion (mL/min)	203.3 ± 89.6**	229.5 ± 95.0**	191.5 ± 87.2**	0.021
Δ cCS flow (mL/min)	125.9 ± 75.8	147.2 ± 77.7	112.4 ± 73.7	0.011
Coronary flow reserve	2.75 ± 1.03	2.91 ± 0.98	2.54 ± 1.00	0.038
CVR at rest, mmHg‧min/mL	1.37 ± 0.54	1.33 ± 0.60	1.41 ± 0.47	0.73
CVR during ATP infusion mmHg‧min/mL	0.49 ± 0.26**	0.44 ± 0.26**	0.53 ± 0.25**	0.049

Data are expressed as mean ± SD. * P-value represents significance of the difference between low EPA group and high EPA group. ** P < 0.05 vs. at rest.
HR = heart rate, ATP = adenosine triphosphate. SBP = systolic blood pressure, DBP = diastolic blood pressure, RPP, rate pressure product; ATP, adenosine triphosphate; EPA, eicosapentaenoic acid; CS, coronary sinus, CVR = coronary vascular resistance.
cCS flow = corrected coronary sinus flow, Ι cCS flow = cCS flow during ATP infusion – cCS flow at rest. Coronary flow reserve = cCS flow during ATP infusion / cCS flow at rest × 100. MAP = (SBP + DBPx2)/3, CVR = MAP/cCS flow.

ISSN: 1532-429X