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Table 3 Coronary sinus blood flow at rest and during ATP infusion in groups with low and high EPA

From: Relationship between coronary flow reserve evaluated by phase-contrast cine cardiovascular magnetic resonance and serum eicosapentaenoic acid

  All patients, (N = 127) High EPA group, (n = 64) Low EPA group, (n = 63) * P-value
HR at rest, bpm 68 ± 12 66 ± 11 70 ± 14 0.14
HR during ATP infusion, bpm 71 ± 12 69 ± 11 73 ± 12 0.086
SBP at rest, mmHg 138 ± 21 136 ± 19 140 ± 22 0.22
SBP during ATP infusion, mmHg 117 ± 20** 117 ± 19** 117 ± 22** 1.00
DBP at rest, mmHg 71 ± 13 69 ± 13 72 ± 12 0.33
DBP during ATP infusion, mmHg 62 ± 12** 62 ± 13** 72 ± 12** 0.87
RPP at rest 9432 ± 2505 9047 ± 2206 9825 ± 2739 0.11
RPP during ATP infusion 8303 ± 2105** 8116 ± 2111** 8508 ± 2100** 0.34
cCS flow at rest (mL/min) 77.4 ± 32.7 82.3 ± 35.0 79.1 ± 32.4 0.59
cCS flow during ATP infusion (mL/min) 203.3 ± 89.6** 229.5 ± 95.0** 191.5 ± 87.2** 0.021
Δ cCS flow (mL/min) 125.9 ± 75.8 147.2 ± 77.7 112.4 ± 73.7 0.011
Coronary flow reserve 2.75 ± 1.03 2.91 ± 0.98 2.54 ± 1.00 0.038
CVR at rest, mmHg‧min/mL 1.37 ± 0.54 1.33 ± 0.60 1.41 ± 0.47 0.73
CVR during ATP infusion mmHg‧min/mL 0.49 ± 0.26** 0.44 ± 0.26** 0.53 ± 0.25** 0.049
  1. Data are expressed as mean ± SD. * P-value represents significance of the difference between low EPA group and high EPA group. ** P < 0.05 vs. at rest.
  2. HR = heart rate, ATP = adenosine triphosphate. SBP = systolic blood pressure, DBP = diastolic blood pressure, RPP, rate pressure product; ATP, adenosine triphosphate; EPA, eicosapentaenoic acid; CS, coronary sinus, CVR = coronary vascular resistance.
  3. cCS flow = corrected coronary sinus flow, Ι cCS flow = cCS flow during ATP infusion – cCS flow at rest. Coronary flow reserve = cCS flow during ATP infusion / cCS flow at rest × 100. MAP = (SBP + DBPx2)/3, CVR = MAP/cCS flow.