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Table 4 Predictors of coronary flow reserve >2.5 determined by univariate and multivariate analyses

From: Relationship between coronary flow reserve evaluated by phase-contrast cine cardiovascular magnetic resonance and serum eicosapentaenoic acid

 

Univariate analysis

Multivariate analysis

Odds ratio

95% CI

P value

Odds ratio

95% CI

P value

Patients’ characteristics

      

  Age, per year

1.01

0.97 – 1.05

0.65

Not selected

  

  Male, men

1.58

0.43 – 5.68

0.49

Not selected

  

  Systolic blood pressure, per mmHg

0.99

0.97 – 1.01

0.99

Not selected

  

  Diastolic blood pressure, per mmHg

0.98

0.95 – 1.02

0.31

Not selected

  

  Heart rate. Per bpm

0.98

0.95 – 1.01

0.19

Not selected

  

  History of myocardial infarction , yes

1.27

0.57 – 2.86

0.55

Not selected

  

  History of angina pectoris, yes

1.56

0.71 – 3.56

0.26

Not selected

  

Coronary risk factors

      

  Hypertension, yes

0.69

0.26 – 0.69

0.45

Not selected

  

  Dyslipidemia, yes

0.67

0.25 – 1.77

0.42

Not selected

  

  Diabetes Mellitus, yes

0.35

0.16 – 0.77

0.009

0.39

0.17 - 0.89

0.026

  Current smoking, yes

1.49

0.50 – 4.45

0.48

Not selected

  

  Family history of CAD, yes

1.21

0.23 – 6.40

0.82

Not selected

  

  Obesity, BMI ≥ 25 kg/m2, yes

1.41

0.66 – 3.00

0.37

Not selected

  

Blood testing

      

  EPA, per μg/mL

1.01

1.00 – 1.02

0.017

1.01

1.00 – 1.02

0.008

  Total cholesterol, per mmol/L

1.00

0.99 – 1.01

0.62

Not selected

  

  LDL cholesterol, per mmol/L

1.00

0.99 – 1.01

0.93

Not selected

  

  HDL cholesterol, per mmol/L

1.02

0.99 – 1.04

0.21

Not selected

  

  Triglyceride, per mmol/L

1.00

0.99 – 1.00

0.97

Not selected

  

  HbA1c, per%

0.92

0.63 – 1.34

0.68

Not selected

  

  eGFR, per mL/min/1.73 m2

0.99

0.97 – 1.03

0.94

Not selected

  

  CRP, per mg/dL

0.57

0.18 – 1.80

0.34

Not selected

  

  BNP, per pg/dl

1.00

0.99 – 1.01

0.66

Not selected

  

Cine CMR

      

  LVEDVI, per mL/m2

1.00

0.99 – 1.01

0.75

Not selected

  

  LVESVI, per mL/m2

0.99

0.98 – 1.01

0.32

Not selected

  

  LVEF, per%

1.03

1.00 – 1.06

0.066

Not selected

  

  LVMI, per g/m2

0.97

0.95 – 1.00

0.019

0.97

0.95-0.99

0.024

Late Gadolinium enhanced CMR

      

  Presence of LGE, yes

0.65

0.32 – 1.32

0.24

Not selected

  

  LGE (%), per%

0.97

0.95 – 1.02

0.35

Not selected

  
  1. The variables with p value < 0.05 in the univariate analysis were included in the multivariate analysis.
  2. CI, confidence interval; CFR, coronary flow reserve; LGE, late gadolinium enhancement; BMI, body mass index; EPA, eicosapentaenoic acid; LDL; low density lipoprotein; HDL, high density lipoprotein, eGFR, estimated glomerular filtration rate; CRP, C-reactive protein; BNP, brain natriuretic peptide; CMR, cardiovascular magnetic resonance; LV, left ventricle; EDVI, end-diastolic volume index; ESVI, end-systolic volume index; SVI, stroke volume index; EF, ejection fraction; LVMI, left ventricular mass index.