Prevalence and distribution of late gadolinium enhancement in a large population of patients with Duchenne muscular dystrophy: effect of age and left ventricular systolic function

Table 4 CMR findings between patients with no septal LGE and those with septal LGE involvement

Patient groups	No septal involvement (n = 96)	Septal involvement (n = 17)	P-value
Age (years)	14.6 ± 4.9^*	18.3 ± 5.5	0.006
Heart rate (bmp)	97.5 ± 16.7	97.3 ± 7.9	0.97
BSA (m²)	1.4 ± 0.32	1.5 ± 0.29	0.22
LVEF (%)	59.5 ± 8.3^*	42.6 ±16.9	<0.0001
LVEDV/BSA (mL/m²)	72.7 ± 17.1^*	111.2 ±44.1	<0.0001
LVM/BSA	51.3 ± 12.7^*	61.1 ± 15.2	0.006
NPS with LGE	4.2 ± 2.2^*	9.4 ± 3.1	<0.0001
Age < 10 years (n = 14)	--------------	7.1% (95% CI, 0.18-33.9)	0.001
Age 10 – 15 years (n = 51)	--------------	7.8% (95% CI, 2.2-18.9)	<0.0001
Age > 15 years ( n = 48)	--------------	25.0% (95% CI, 13.6-39.6)	0.0005

Abbreviations: BSA Body Surface Area, BMP Beats per minute, CI Confidence Interval, CMR Cardiovascular Magnetic Resonance, LGE Late Gadolinium Enhancement, LVEF Left Ventricular Ejection Fraction, LVEDV Left Ventricular End-Diastolic Volume, LVM Left Ventricular Mass, mL Milliliter, m² Meter Square, n Number of patients, NPS Number of Positive Segments, * = P value (<0.05) is significant.

ISSN: 1532-429X