Table 1 Clinical and cardiac magnetic resonance imaging characteristics of 47 patients with isolated ventricular non-compaction
Total patients (n =47) | LGE status | |||
|---|---|---|---|---|
LGE(+) (n =19) | LGE(-) (n =28) | P-value | ||
Age (yrs) | 39 ± 18 | 43 ± 14 | 36 ± 20 | 0.16 |
Gender male, n (%) | 37 (79%) | 13 (68%) | 24 (86%) | 0.16 |
Weight (kg) | 67 ± 16 | 68 ± 16 | 66 ± 15 | 0.65 |
NYHA functional class III/IV | 42 (89%) | 19 (100%) | 23 (82%) | 0.07 |
Symptoms | ||||
Chest pain, n (%) | 5 (11%) | 2 (11%) | 3 (11%) | 0.98 |
Syncope, n (%) | 4 (9%) | 2 (11%) | 2 (7%) | 0.68 |
Systemic thrombo-embolism | 3(6%) | 1 (5%) | 2 (7%) | 0.80 |
Electrocardiogram | ||||
Left bundle branch block | 7 (15%) | 3 (16%) | 4 (14%) | 0.89 |
Right bundle branch block | 5 (11%) | 2 (11%) | 3 (11%) | 0.98 |
Atrial fibrillation | 10 (21%) | 4 (21%) | 6 (21%) | 0.98 |
24 h ambulatory Holter ECG | ||||
PVCs | 49% | 79% | 29% | 0.001 |
NSVT | 23% | 47% | 7% | 0.003 |
Non-compacted segments per patient | 7.4 ± 2.5 | 6.9 ± 1.9 | 7.8 ± 2.7 | 0.26 |
Non-compacted/compacted ratio | 3.2 ± 0.7 | 3.0 ± 0.6 | 3.4 ± 0.7 | 0.09 |
CMR Parameters | ||||
LV end-diastolic diameter (mm) | 69 ± 10 | 69 ± 9 | 69 ± 11 | 0.92 |
LV end-diastolic volume (ml) | 243 ± 97 | 250 ± 90 | 239 ± 103 | 0.67 |
LV end-systolic volume (ml) | 189 ± 94 | 198 ± 88 | 179 ± 99 | 0.50 |
LV ejection fraction (%) | 27 ± 13 | 23 ± 8 | 29 ± 15 | 0.06 |
LV mass (g) | 124 ± 44 | 135 ± 50 | 117 ± 38 | 0.17 |