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Table 1 Haemodynamics in young and older mice

From: Heterogeneous abnormalities of in-vivo left ventricular calcium influx and function in mouse models of muscular dystrophy cardiomyopathy

  YOUNG OLD
  WT Mdx Sgcd−/− WT Mdx Sgcd−/−
N 11 10 10 7 9 13
Body weight, g 33.3±0.9* 35.8±1.0** 28.8±1.0 40.5±1.2** 37.1±1.1 32.9±0.9
Heart rate, bpm 390±13** 419±14 480±14 384±16** 427±15 483±12
LV mass index, (×10 -3 ) 3.03±0.12 3.57±0.13 3.58±0.13 2.80±0.14** 3.56±0.13+ 3.86±0.11
EDV index, μl/g 1.97±0.11 1.72±0.11 2.06±0.11 1.93±0.14 1.78±0.12 1.94±0.10
ESV index, μl/g 0.70±0.07 0.68±0.08 0.67±0.08 0.72±0.09 0.74±0.08 0.69±0.07
Stroke volume index, μl/g 1.28±0.06 1.03±0.06**/ 1.38±0.06 1.21±0.07 1.04±0.06 1.25±0.05
Ejection fraction, % 65±2 61±2†† 68±2 63±3 60±2†† 65±2
Cardiac index, ml/min/g 0.50±0.03** 0.43±0.03** 0.67±0.03 0.46±0.03# 0.44±0.03** 0.60±0.03
  1. LV: left ventricle; EDV: end-diastolic volume; ESV, end-systolic volume.
  2. *P<0.01 vs older WT.
  3. **P<0.01 vs Sgcd−/− within same age group.
  4. +P<0.05 vs WT within same age group.
  5. #P=0.06 vs Sgcd−/− within same age group.
  6. P<0.01 ANOVA vs WT and Sgcd−/− both ages combined.
  7. ††P<0.05 ANOVA vs Sgcd−/− both ages combined.