Figure 8

Anatomical images of a representative subject, one axial slice and zoomed in insert on the right common carotid artery (bottom left of all panels). Panel A, SHILO low spatial/high temporal resolution image for AIF acquisition. Red star in insert, ROI used to sample blood SI curve. Panel B, SHILO high spatial/low temporal resolution image for tissue data acquisition. In the insert, the ROIs used to sample the muscle (green) and vessel wall (blue) SI curves are depicted. Panel C: red line, AIF from low spatial/high temporal resolution SHILO; blue dots, vessel wall SI curve from high spatial/low temporal resolution SHILO; green dots, muscle SI curve from high spatial/low temporal resolution SHILO. Blue and green lines represent kinetic modeling fittings. X axis, time (min). Y axis, contrast agent concentration (mmol/l). Vessel wall and muscle curves are plotted 25 times their measured concentrations for clarity in the plot.