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Table 2 Minimum dataset of parameters that will be able to be derived from images acquired in UK Biobank CMR protocol

From: Imaging in population science: cardiovascular magnetic resonance in 100,000 participants of UK Biobank - rationale, challenges and approaches

Cardiovascular structure

Quantifiable parameters

Left ventricle

Myocardial mass (g), ejection fraction (%), end-diastolic volume (ml), end-systolic volume (ml), stroke volume (ml) and the corresponding values indexed to body surface area, height or weight. Time to peak contraction and filling rates (both in s) and peak contraction and filling rates (both in ml/s). American Heart Association (AHA) myocardial segments: end-diastolic thickness (mm), end-systolic thickness (mm), thickening (mm), thickening (%). Strain: strain (%) and strain-rates (1/s) in three directions (radial [ERR], circumferential [ECC] and longitudinal [ELL]) and in systole and diastole and corresponding changes in angle caused by shear (ERC, ERL and ECL).

Right ventricle

Myocardial mass (g), ejection fraction (%), end-diastolic volume (ml), end-systolic volume (ml), stroke volume (ml) and the corresponding values indexed to body surface area, height or weight.

Left atrium

End-diastolic volume (ml), end-systolic volume (ml), stroke volume (ml), ejection fraction (ml) and left atrial diameters as typically measured by 2D-echocardiography approaches.

Right atrium

End-diastolic volume (ml), end-systolic volume (ml), stroke volume (ml), ejection fraction (ml) and right atrial diameters as typically measured by 2D-echocardiography approaches.

Aorta

Distensibility (1/mmHg) in ascending aorta, proximal descending and distal descending aorta; diastolic aortic dimensions (cm2): ascending aorta, proximal descending and distal descending aorta. Proximal, distal and total pulse wave velocity (m/s).