Prediction of aortic dilation in Turner syndrome - enhancing the use of serial cardiovascular magnetic resonance

Table 3 Percentage change in aortic diameter due to one unit increase in the variables influencing aortic diameter (based on the findings in Table 2 )

Variable	COARC	Age	BITRI	Antihypertensive treatment	Diastolic ABP	BSA	ERT duration	ETA
position	COARC	Age	BITRI	Antihypertensive treatment	Diastolic ABP	BSA	ERT duration	ETA
Aortic sinus	4.42	0.30	10.39	−4.02	−0.62	1.62	0.20	3.64
Sinotubular junction	−1,54	0.31	13.76	−0.74	−0.53	0.54	0.17	1.67
Mid-ascending aorta	−5.81	0.60	19.03	−0.99	0.78	0.52	−0.03	1.15
Distal ascending aorta	−3.10	0.45	8.12	0.31	0.84	0.96	−0.22	0.00
Proximal aortic arch	−6.73	0.34	8.39	−1.15	0.10	1.68	−0.31	−1.07
Mid aortic arch	−5.66	0.09	0.80	−0.77	0.86	1.49	−0.09	−4.45
Distal transverse aortic arch	−1.70	0.26	2.41	0.55	1.64	1.81	−0.06	−2.39
Proximal descending	23.40	0.07	5.19	−1.39	0.86	1.14	0.01	0.37
Distal descending aorta	14.43	0.34	4.77	1.00	1,37	1.94	−0.08	−1.62
P value	<0.0001	<0.0001	0.0004	0.005	0.0008	0.02	0.08	0.4

For BITRI, ETA and antihypertensive treatment we present the percentage change in diameter in the presence of these variables (in contrast to the normal condition of a tricuspid valve, no ETA and no antihypertensive treatment). For ERT duration we examined the additive effect of one additional year of treatment. For diastolic blood pressure we examined the percentage change in the aortic diameter due to a 10 mmHg increase and for BSA due to 10% increase. The p-value indicates whether the parameter influences the thoracic aorta at any point.
Abbreviations: COARC aortic coarctation, BITRI the presence of a bicuspid aortic valve, ABP ambulatory blood pressure, BSA Body surface area, ERT oestrogen replacement, ETA elongated transverse aortic arch.

ISSN: 1532-429X