Figure 1From: Diffuse myocardial fibrosis by T1-mapping in children with subclinical anthracycline cardiotoxicity: relationship to exercise capacity, cumulative dose and remodelingSASHA T 1 mapping method in a subject 15 minutes post-contrast. On each of 10 saturation recovery images, the endocardium, epicardium and a region of interest in the blood are selected. The myocardium is automatically divided into 18 circumferential segments and T1 values are calculated in each segment by fitting a recovery curve as described in the methods. Average signal intensity in a septal segment (white box, far right image) are shown along with a best-fit saturation recovery curve. S is the measured signal intensity normalized to the non-saturated image intensity, η is the best-fit saturation efficiency, TS are saturation recovery times and T1 is the best fit T1 value.Back to article page