Figure 4From: Understanding cardiovascular injury after treatment for cancer: an overview of current uses and future directions of cardiovascular magnetic resonanceSerial changes in LV volumes, myocardial strain and LVEF after anthracycline exposure in human subjects. Time dependent changes in left ventricular (LV) end diastolic volume (left y-axis; panel A) and LV end systolic volume (right y-axis; panel A); in LV ejection fraction (left y-axis; panel B); serum Troponin-I (right y-axis; panel B); pulse wave velocity (PWV) (left y-axis; panel C); and mean mid wall circumferential strain (right y-axis; panel C). The mean ± the standard error are shown. There was a substantive increase in LV end systolic volume, PWV, and serum Troponin-I while at the same time a decrease in LV ejection fraction and mean mid-wall circumferential strain from baseline to six months after administration of low to moderate doses of anthracycline-based chemotherapy. Reprinted from Drafts, et al. JACC-Imaging 2012[96].Back to article page