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Figure 4 | Journal of Cardiovascular Magnetic Resonance

Figure 4

From: Understanding cardiovascular injury after treatment for cancer: an overview of current uses and future directions of cardiovascular magnetic resonance

Figure 4

Serial changes in LV volumes, myocardial strain and LVEF after anthracycline exposure in human subjects. Time dependent changes in left ventricular (LV) end diastolic volume (left y-axis; panel A) and LV end systolic volume (right y-axis; panel A); in LV ejection fraction (left y-axis; panel B); serum Troponin-I (right y-axis; panel B); pulse wave velocity (PWV) (left y-axis; panel C); and mean mid wall circumferential strain (right y-axis; panel C). The mean ± the standard error are shown. There was a substantive increase in LV end systolic volume, PWV, and serum Troponin-I while at the same time a decrease in LV ejection fraction and mean mid-wall circumferential strain from baseline to six months after administration of low to moderate doses of anthracycline-based chemotherapy. Reprinted from Drafts, et al. JACC-Imaging 2012[96].

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