Early detection of subclinical ventricular deterioration in aortic stenosis with cardiovascular magnetic resonance and echocardiography

Table 2 Echocardiographic parameters of the study participants

	Total (n = 118)	Group 1 (n = 54)	Group 2 (n = 45)	Group 3 (n = 19)	p-value
LVEDD (mm)	51 (5)	49 (5)	50 (5)	59 (7)^‡	<0.001
LVESD (mm)	33 (8)	30 (4)	31 (4)	46 (9)^‡	<0.001
IVST (mm)	12 (5)	11 (2)	13 (6)^*	13 (6)	0.080
PWT (mm)	11 (2)	10 (2)	11 (2)^*	11 (2)	0.036
Aortic annulus diameter (mm)	21 (2)	21 (2)	21 (3)	22 (3)	0.902
E (m/sec)	0.77 (0.28)	0.73 (0.23)	0.79 (0.28)	0.83 (0.40)	0.386
DT (m/sec)	252 (78)	246 (71)	270 (81)	226 (85)^†	0.088
e’ (cm/sec)	4.8 (1.6)	5.3 (1.7)	4.7 (1.3)	3.9 (1.6)^†	0.005
Vmax (m/sec)	4.7 (0.8)	4.6 (0.8)	4.9 (0.8)^*	4.3 (0.7)^‡	0.015
AVA (cm²)	0.76 (0.21)	0.79 (0.20)	0.75 (0.21)	0.70 (0.25)	0.291
AVA index (cm²/m²)	0.46 (0.13)	0.48 (0.13)	0.45 (0.12)	0.43 (0.14)	0.234
Transaortic mean PG (mmHg)	54 (22)	52 (21)	59 (19)	50 (28)	0.152

The data are presented as mean (SD). The difference of each parameters between the three groups was calculated using analysis of variance (ANOVA) and between the two groups with Student’s t-test and the results presented as p-value. LV, left ventricle; EDD/ESD, end-diastolic/systolic diameter; IVST, interventricular septal thickness; PWT, posterior wall thickness; E, early diastolic velocity at mitral valve tip; DT, deceleration time; e’, early mitral annular velocity at the septal annulus; Vmax, maximal transaortic velocity; AVA, aortic valve area; PG, pressure gradient.^*p < 0.01 versus group 1, ^†p < 0.01 versus group 2,^‡p < 0.05 versus group 2.

ISSN: 1532-429X