Figure 6
Application of shape correction to the analysis of myocardial infarction. a) Hotelling’s T2 for the infero-lateral DETERMINE subcohort (N = 27) compared to the MESA cases (N = 300) without any protocol-bias correction. b) Hotelling’s T2 statistic after the protocol-bias correction. Red shows most significant differences while blue represents least significant differences. The papillary muscle significant difference due to protocol bias disappears after correction. Viewpoint is from the lateral wall: the arrow points from the center of the blood pool toward the septum.