Figure 6

Relationship between right pulmonary arterial diameter and WSS with BSA in controls and subjects with pulmonary arterial hypertension. (a) RPA diameter and WSS measurements in systole demonstrate a BSA dependence in both cohorts. The white line indicates the regression model (y = ax^0.5) for the control group, with the blue shaded region indicating the 95% confidence region; the dashed line indicates results (n = 496) from Sluysman et al. [26]. (b) WSS decreases rapidly as a function of the BSA-indexed RPA diameter. Solid markers indicate subjects with cross-sectional profiles plotted in Figure 2. The regression line in (b) is an inverse cubic regression, reflecting the inverse proportional relationship between WSS and the vessel radius cubed. Note: diameter measurements are augmented with data collected in previous echo-based studies [33]; WSS measurements are from CMR-only.