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Table 1 Demographics and flow quantification of PAH study patients

From: Wall shear stress measured by phase contrast cardiovascular magnetic resonance in children and adolescents with pulmonary arterial hypertension

 

Control (n = 4)

PAH (n = 25)

P

Age, (y)

19 ± 12

12 ± 5

0.3

Sex, (M:F)

2:2

11:14

 

BSA (m 2 )

1.7 ± 0.7

1.2 ± 0.3

0.14

RPA diam (cm)

1.2 ± 0.5

1.8 ± 0.7

0.19

RPA/ BSA (cm/m 2 )

0.7 ± 0.1

1.5 ± 0.4

0.003

RAC (%)

32 ± 18

21 ± 11

0.15

Vmean t_ avg (cm/s)

30 ± 12

17 ± 11

0.05

V mean systole (cm/s)

83 ± 23

58 ± 34

0.07

Q avg (L/min)

2.6 ± 1.2

2.4 ± 1.0

0.55

Qsys (L/min)

9.0 ± 4.4

8.9 ± 3.7

0.68

V max (m/s)

1.3 ± 0.7

0.8 ± 0.5

0.14

RF(%)

0.9 ± 0.9

1.1 ± 2.0

0.47

WSS t_avg (dyne/cm2)

−6.6 ± 3.4

−2.2 ± 1.6

0.018

  1. Values are mean ± SD; PAH = pulmonary arterial hypertension; BSA = body surface area (m2); RPA = right pulmonary artery diameter (cm); RPA/BSA = normalized RPA diameter (cm/m2); RAC = Relative Area Change (%); Vmeant_avg = time-averaged mean velocity over vessel cross-section; Vmeansystole = systolic mean velocity over vessel cross-section; Qavg = average flow rate (L/min); Qsys = peak systolic flow rate (L/min); RF = regurgitant fraction (%); Vmax = max velocity (m/s); WSSt_avg = circumferentially averaged WSS over cardiac cycle.