| |
Control (n = 4)
|
PAH (n = 25)
|
P
|
|---|
|
Age, (y)
|
19 ± 12
|
12 ± 5
|
0.3
|
|
Sex, (M:F)
|
2:2
|
11:14
| |
|
BSA (m
2
)
|
1.7 ± 0.7
|
1.2 ± 0.3
|
0.14
|
|
RPA diam (cm)
|
1.2 ± 0.5
|
1.8 ± 0.7
|
0.19
|
|
RPA/ BSA (cm/m
2
)
|
0.7 ± 0.1
|
1.5 ± 0.4
|
0.003
|
|
RAC (%)
|
32 ± 18
|
21 ± 11
|
0.15
|
|
Vmean
t_ avg
(cm/s)
|
30 ± 12
|
17 ± 11
|
0.05
|
|
V
mean
systole
(cm/s)
|
83 ± 23
|
58 ± 34
|
0.07
|
|
Q
avg (L/min)
|
2.6 ± 1.2
|
2.4 ± 1.0
|
0.55
|
|
Qsys (L/min)
|
9.0 ± 4.4
|
8.9 ± 3.7
|
0.68
|
|
V
max
(m/s)
|
1.3 ± 0.7
|
0.8 ± 0.5
|
0.14
|
|
RF(%)
|
0.9 ± 0.9
|
1.1 ± 2.0
|
0.47
|
|
WSS
t_avg
(dyne/cm2)
|
−6.6 ± 3.4
|
−2.2 ± 1.6
|
0.018
|
- Values are mean ± SD; PAH = pulmonary arterial hypertension; BSA = body surface area (m2); RPA = right pulmonary artery diameter (cm); RPA/BSA = normalized RPA diameter (cm/m2); RAC = Relative Area Change (%); Vmeant_avg = time-averaged mean velocity over vessel cross-section; Vmeansystole = systolic mean velocity over vessel cross-section; Qavg = average flow rate (L/min); Qsys = peak systolic flow rate (L/min); RF = regurgitant fraction (%); Vmax = max velocity (m/s); WSSt_avg = circumferentially averaged WSS over cardiac cycle.
