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Table 1 Subject characteristics

From: Pulmonary blood volume indexed to lung volume is reduced in newly diagnosed systemic sclerosis compared to normals – a prospective clinical cardiovascular magnetic resonance study addressing pulmonary vascular changes

Characteristics

SSc

Controls

Total (n)

27

10

Male:female ratio

3:6

3:7

Age (y)

57 ± 13

54 ± 9

Body surface area (BSA, m2)

1.81 ± 0.16

1.78 ± 0.21

Heart rate (bpm)

76 ± 11

64 ± 7 †

Cardiac index (L/min/m2)

3.3 ± 0.8

3.5 ± 0.6

LV stroke volume index (mL/m2)

44 ± 11

54 ± 7

LV end diastolic volume index (mL/m2)

72 ± 16

89 ± 10

LV end systolic volume index (mL/m2)

29 ± 9

35 ± 4

LV ejection fraction (%)

61 ± 8

60 ± 3

RV stroke volume index (mL/m2)

42 ± 8

53 ± 7 ‡

RV end diastolic volume index (mL/m2)

79 ± 23

83 ±11

RV end systolic volume index (mL/m2)

37 ± 22

30 ± 7

RV ejection fraction (%)

55 ± 13

64 ± 6

Duration of disease (y)

6 ± 8

 

Limited cutaneous SSc (n (%))

18 (67)

 

Diffuse cutaneous SSc (n (%))

3 (11)

 

Early SSc (n (%))

6 (22)

 

PAH (n (%))

1 (4)

 
  1. LV denotes left ventricle, RV denotes right ventricle. Bpm denotes beats per minute. Disease duration was calculated from first non-Raynaud's manifestation. Early SSc denotes patients fulfilling the LeRoy criteria. PAH denotes pulmonary arterial hypertension verified by right heart catheterization (defined as mPAP >25 mmHg). Data are presented as mean ± SD. † denotes p < 0.01, and ‡ denotes p < 0.001 compared to patients with systemic sclerosis (SSc).