Table 1 Blood pressure, renal volumes and hemodynamic parameters in renal artery stenosis (RAS) or control mice
| Â | Baseline | 2 weeks | 4 weeks |
|---|---|---|---|
Blood pressure (mmHg) | Â | Â | Â |
  RAS MAP | 80 ± 1 | 112 ± 5*$# | 118 ± 5*$# |
     Diastolic | 72 ± 2 | 99 ± 4*$# | 106 ± 5*$# |
     Systolic | 98 ± 3 | 138 ± 6*$# | 144 ± 6*$# |
  Control MAP | 83 ± 1 | 78 ± 1 | 83 ± 3 |
     Diastolic | 76 ± 2 | 69 ± 2 | 76 ± 4 |
     Systolic | 97 ± 2 | 96 ± 4 | 99 ± 2 |
Body weight (g) | Â | Â | Â |
     RAS | 20.7 ± 0.7 | 19.0 ± 1.2*$# | 21.1 ± 1.1# |
     Control | 21.0 ± 0.9 | 23.2 ± 0.7* | 23.8 ± 0.6* |
Volume (mm3) | Â | Â | Â |
  Stenotic Kidney |  |  |  |
     Cortex | 141 ± 8 | 86 ± 8*$# | 91 ± 8*$# |
     Medulla | 47 ± 2 | 23 ± 4*$# | 18 ± 3*$# |
  Contralateral Kidney |  |  |  |
     Cortex | 140 ± 7 | 158 ± 7 | 179 ± 8*$# |
     Medulla | 46 ± 3 | 42 ± 5 | 38 ± 3*# |
  Control |  |  |  |
     Cortex | 135 ± 5 | 140 ± 3 | 146 ± 6 |
     Medulla | 44 ± 3 | 42 ± 2 | 51 ± 3 |
Flow (μl/min) |  |  |  |
  Stenotic Kidney |  |  |  |
     Cortex | 613 ± 48 | 224 ± 35*$# | 194 ± 35*$# |
     Medulla | 75 ± 5 | 24 ± 6*$# | 18.0 ± 4*$# |
     RBF | 688 ± 46 | 248 ± 40*$# | 212 ± 39*$# |
  Contralateral Kidney |  |  |  |
     Cortex | 643 ± 50 | 650 ± 35 | 728 ± 52 |
     Medulla | 73 ± 4 | 62 ± 10 | 55 ± 8# |
     RBF | 716 ± 49 | 712 ± 41 | 783 ± 56 |
  Control |  |  |  |
     Cortex | 611 ± 18 | 680 ± 21 | 650 ± 35 |
     Medulla | 77 ± 5 | 74 ± 5 | 83 ± 6 |
     RBF | 688 ± 18 | 754 ± 24* | 733 ± 40 |
Perfusion (ml/100Â g/min) | Â | Â | Â |
  Stenotic Kidney |  |  |  |
     Cortex | 434 ± 22 | 239 ± 27*$# | 194 ± 30*$# |
     Medulla | 168 ± 18 | 90 ± 11*$# | 85 ± 15*$# |
  Contralateral Kidney |  |  |  |
     Cortex | 458 ± 22 | 416 ± 16# | 409 ± 24 |
     Medulla | 165 ± 13 | 139 ± 13# | 134 ± 17 |
  Control |  |  |  |
     Cortex | 455 ± 12 | 487 ± 10 | 443 ± 14†|
     Medulla | 173 ± 5 | 176 ± 10 | 163 ± 6 |