| Normal controls N=39 | Controls with CVRFs N=11 | SLE N=11 | SLE with CVRF N=19 | P Value |
---|---|---|---|---|---|
Mid SA systolic circumferential strain | -19.4 ± 1.1 | -18.4 ± 1.4 | -16.7 ± 1.2 | 16.3 ± 1.0 | <0.001 |
Peak diastolic strain rate | 144.5 ± 14.5 | 126.9 ± 20.7 | 99.6 ± 23.2 | 89.4 ± 17.3 | <0.001 |
Aortic distensibility (10-3mmHg-1) Ascending aorta Proximal descending aorta Distal descending aorta | 3.6 ± 2.0 4.1 ± 1.5 6.2 ± 2.5 | 3.1 ± 1.9 3.4 ± 1.7 4.7 ± 1.8 | 3.2 ± 1.1 3.8 ± 1.0 5.0 ± 1.2 | 2.4 ± 1.2 2.8 ± 1.0 3.6 ± 1.2 | 0.11 0.006 <0.001 |
Pulse wave velocity (m/s) Aortic arch PWV Descending aorta PWV Total PWV | 4.2 ± 2.0 3.7 ± 1.5 4.3 ± 1.4 | 5.5 ± 1.9 5.9 ± 1.6 5.4 ± 2.4 | 6.0 ± 1.2 6.6 ± 1.6 6.3 ± 1.3 | 7.5 ± 2.1 8.1 ±1.7 8.5 ± 1.9 | <0.001 <0.001 <0.001 |