Table 1 Gender Specific Effects of Obesity on Regional Aortic Diameter - Data Presented as Mean With Normal Range (+/- 2SD)

Aortic Diameter (mm)

Normal Weight

Overweight

Obese

ANOVA p

Aortic Valve Annulus

24.0 (18.8-29.2)

24.7 (19.5-29.9)

25.7 (20.7-30.7)

<0.05

Sinus of Valsalva

32.2 (24.6-39.8)

32.9 (25.3-40.5)

33.3 (25.3-31.3)

<0.05

Sino-tubular Junction

24.9 (18.1-31.7)

25.8 (17.0-34.6)

25.9 (19.1-32.7)

<0.05

Ascending Aorta

26.6 (18.2-35.0)

27.8 (18.8-36.8

28.6 (23.2-34.0)

<0.01

Proximal Descending Aorta

20.4 (14.6-26.2)

21.2 (15.6-26.8)

22.1 (16.5-27.7)

<0.01

Distal Descending Aorta

17.4 (12.0-22.8)

18.3 (12.7-23.9)

19.0 (14.8-23.2)

<0.01

BMI (kg/m2)

22 +/-1.7

27 +/-1.6

34 +/-4.8

<0.01

BSA (m2)

1.9 (+/-0.1)

2.0 (+/-0.1)

2.3 (+/-0.2)

<0.01

Female

Aortic Diameter (mm

Normal Weight

Overweight

Obese

ANOVA p

Aortic Valve Annulus

20.2 (17.0-23.4)

21.7 (18.5-23.9)

21.6 (17.6-25.6)

<0.01

Sinus of Valsalva

27.6 (22.0-33.2)

28.6 (21.6-35.6)

27.8 (22.2-33.4)

<0.05

Sino-tubular Junction

21.7 (16.7-26.7)

22.5 (16.5-28.5)

22.3 (16.5-28.1)

<0.05

Ascending Aorta

24.8 (17.6-32.0)

26.7 (19.3-34.1)

26.9 (19.3-34.5)

<0.01

Proximal Descending Aorta

18.6 (14.6-22.6)

19.5 (14.9-24.1)

20.1 (15.5-24.7)

<0.01

Distal Descending Aorta

16.1 (14.1-18.1)

16.9 (14.7-19.1)

17.6 (15.7-19.5)

<0.01

BMI (kg/m2)

22.0 (+/-1.6)

27.0 (+/-1.5)

37.0 (+/-4.8)

<0.01

BSA (m2)

1.7 (+/-0.1)

1.8 (+/-0.1)

2.0 (+/-0.2)

<0.01