Figure 1

Increase in R2* values in control STEMI patients (no USPIO) (blue, n=6), STEMI patients given USPIO (red, n=10) and CABG patients (green, n=32). Most significant R2* increase (and hence myocardial inflammation) observed in infarct zones, with CABG myocardial R2* increase between infarct and myocardium remote to infarction. The spatially registered regions of interests (ROI) for quantifying R2* value for STEMI and CABG patients are shown in the MRI images at the bottom of the figure.