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Table 2 Phosphate Metabolites and Creatine Kinase Flux at Rest and During Plantar Flexion Exercise

From: Skeletal muscle ATP kinetics during exercise in patients with systolic heart failure

  Healthy (n=11) SHF (n=14)
PCr/ATP (rest) 4.42 ± 1.67 5.70± 2.0
PCr/ATP (ex) 3.76 ± 1.73¶ 4.46± 2.2 ¶
k (s-1)(rest) 0.27 ± 0.04 0.29 ± 0.05
k (s-1)(ex) 0.35 ± 0.11 * 0.35 ± 0.06 *
PCr (µmol/g) (rest) 22.9 ± 8.7 29.4 ± 10.9
PCr (µmol/g)(ex) 18.8 ± 9.7 § 22.2 ± 9.8 §
CK flux (µmol.g-1.s-1)(rest) 6.37 ± 3.15 8.53 ± 2.96
CK flux (µmol.g-1.s-1) (ex) 6.68 ± 4.44 7.57 ± 2.62*
  1. PCr/ATP-phosphocreatine/Adenosine triphosphate ratio; k- CK reaction pseudo first order rate constant; mean±SD, * <0.05 compared to rest; ¶ <0.01 compared to rest, § <0.001 compared to rest