Skip to main content
Figure 2 | Journal of Cardiovascular Magnetic Resonance

Figure 2

From: Molecular assessment of aortic aneurysm wall integrity using an elastin-specific MR imaging probe

Figure 2

In vivo assessment of advanced thrombus remodeling. A: TOF-angiogram of the suprarenal part of the abdominal aorta (A1, A2 fusion with Elastin-MRI scan) 4 weeks after infusion of angiotensin II. On the TOF angiogram the formation of a large aortic aneurysm can be observed. At this late stage the thrombus in the aneurysmal wall is almost completely remodelled with elastin (A6, A11). The locations of rupture of the elastic laminae are still visible (A11, magnification on right side, red arrows). A "novel elastic lamina" is formed on the luminal side of the arterial wall (A11, magnification on left side, red arrow heads). A strong signal can be observed in the area of remodeling on Elastin-MRI (A3-5, A8-10, red arrows). B: Example of a T1 relaxation curve prior to and after administration of the elastin-specific MR imaging probe. A significant shortening of the T1 relaxation time could be measured post injection of the elastin-specific MR imaging probe.

Back to article page