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Table 1 Parameters in Controls vs. HCM Patients

From: Diffuse myocardial fibrosis in pediatric hypertrophic cardiomyopathy

 

Controls (mean ± s.d.)

HCM Patients

p-value (*<0.05)

Number

12

28

 

No. male

7

21

 

Age (yrs.)

12.8 ± 2.2

12.8 ± 2.6

0.95

Septum partition coefficient (ml/g)

0.13 ± 0.09

0.27 ± 0.17

0.03*

Lateral wall partition coefficient (ml/g)

0.07 ± 0.10

0.22 ± 0.09

<0.001*

BNP (pg/ml)

10.1 ± 6.6

283 ± 429

0.009*

Number with LGE

0

8

 

Ejection fraction (%)

57 ± 3

68 ± 10

<0.001*

Indexed myocardial mass (g/m2)

54 ± 7

103 ± 40

<0.001*

  1. Note that the partition coefficients are significantly raised in HCM patients compared with controls. (BNP = Brain Natriuretic Peptide; LGE = Late Gadolinium Enhancement)