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Table 1 Parameters in Controls vs. HCM Patients

From: Diffuse myocardial fibrosis in pediatric hypertrophic cardiomyopathy

  Controls (mean ± s.d.) HCM Patients p-value (*<0.05)
Number 12 28  
No. male 7 21  
Age (yrs.) 12.8 ± 2.2 12.8 ± 2.6 0.95
Septum partition coefficient (ml/g) 0.13 ± 0.09 0.27 ± 0.17 0.03*
Lateral wall partition coefficient (ml/g) 0.07 ± 0.10 0.22 ± 0.09 <0.001*
BNP (pg/ml) 10.1 ± 6.6 283 ± 429 0.009*
Number with LGE 0 8  
Ejection fraction (%) 57 ± 3 68 ± 10 <0.001*
Indexed myocardial mass (g/m2) 54 ± 7 103 ± 40 <0.001*
  1. Note that the partition coefficients are significantly raised in HCM patients compared with controls. (BNP = Brain Natriuretic Peptide; LGE = Late Gadolinium Enhancement)