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Table 2 RV parameters for and SCD and TM pediatric patient without cardiac iron overload, with differentiation for gender. All variables are expressed as mean ± SD with 95% confidence intervals in square brackets.

From: Biventricular dimensions and function in pediatric sickle-cell disease and thalassemia major patients without cardiac iron

 

SCD

TM

P

P adjusted for systolic BP

P adjusted for cardiac R2*

P adjusted for both covariates

Males

RV EDVI (ml/m 2 )

103.3 ± 18.8 [96.8 - 109.8]

87.3 ± 11.5 [82.9 - 91.6]

<0.0001

<0.0001

0.0004

0.0002

RV ESVI (ml/m 2 )

37.9 ± 9.6 [34.7 - 41.2]

32.4 ± 5.7 [30.2 - 34.5]

0.0005

0.006

0.050

0.037

RV SVI (ml/m 2 )

65.4 ± 10.8 [61.6 - 69.1]

54.9 ± 6.9 [52.3 - 57.5]

<0.0001

0.016

<0.0001

<0.0001

RV EF (%)

63.8 ± 4.7 [62.2 - 65.4]

63.2 ± 3.4 [61.9 - 64.5]

0.620

   

Females

RV EDVI (ml/m 2 )

84.7 ± 10.3 [80.9 - 88.5]

76.5 ± 9.1 [72.4 - 80.6]

0.005

0.026

0.009

0.051

RV ESVI (ml/m 2 )

31.1 ± 5.8 [28.9 - 33.2]

27.7 ± 5.3 [25.3 - 30.1]

0.037

0.108

  

RV SVI (ml/m 2 )

53.6 ± 6.8 [51.1 - 56.1]

48.8 ± 5.1 [46.6 - 51.1]

0.006

0.047

  

RV EF (%)

63.6 ± 4.6 [61.9 - 65.2]

64.4 ± 3.7 [62.7 - 66.1]

0.477

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