Figure 1

Illustration of the spatial autocorrelation statistic, Moran's I, which describes the distribution of values in a volume in relation to their difference from the mean value and proximity to other voxels of similar intensity value. Moran's I ranges from I=-1 (diffuse distribution) to I=+1 (clustered distribution) and I=0 represents random distribution in the volume of values different from the mean value. Each illustration in the image contains the same number of white dots (or mean value) but different patterns of distribution.