Skip to main content

Table 1 The effects of intermediate dose dobutamine compared to exercise stress on left ventricular haemodynamics and strain parameters.

From: Myocardial haemodynamic responses to dobutamine stress compared to physiological exercise during cardiac magnetic resonance imaging

Parameter Stressor Significance
  Rest 1 Rest 2 Exercise Dobutamine Rest 1 vs rest 2 Rest vs exercise Rest vs dobutamine Exercise vs dobutamine
Heart Rate (bpm) 70.2±13.7 68.6±11.9 108±10 116±11 NS <0.05 <0.05 NS
Mean BP (mmHg) 89.4±6.4 91.5±10.2 124±19 103±11 NS <0.05 <0.05 <0.05
CI (l/min/m2) 2.7±0.6 3.0±0.6 4.5±1.1 5.7±0.8 NS <0.05 <0.05 <0.05
EDV (ml/m2) 73.2±15.9 76.9±12.5 72.0±17.2 64.5±11.5 NS NS <0.05 <0.05
ESV (ml/m2) 34.5±9.7 33.4±7.5 25.9±9.4 15.2±5.0 NS <0.05 <0.05 <0.05
SV (ml/m2) 38.6±7.7 43.5±6.5 46.1±8.5 49.3±8.0 NS <0.05 <0.05 NS
EF (%) 53.3±6.3 56.9±4.4 65.0±5.7 76.9±4.6 NS <0.05 <0.05 <0.05
Err (%) 21.3±9.7 19.6±9.2 33.0±16.1 42.3±18.5 NS NS <0.05 NS
Err.tps (ms) 294±62 345±90 267±52 187±34 NS <0.05 <0.05 <0.05
Ecc (%) 22.6±2.9 24.1±2.5 30.6±2.9 39.2±8.3 NS <0.05 <0.05 <0.05
Ecc.tps (ms) 305±64 338±57 288±63 179±20 NS <0.05 <0.05 <0.05
  1. Rest 1= rest prior to exercise study; Rest 2=rest prior to dobutamine study. Left ventricular volumes are indexed for body surface area and results are expressed as mean ± standard deviation. Paired t-test was used to test significance, set at a level of <0.05. CI= cardiac index, EDV=end diastolic volume, ESV=end systolic volume, SV=stroke volume, EF=ejection fraction, Err=short axis radial strain, Err.tps=radial time to peak strain, Ecc=circumferential strain, Ecc.tps=circumferential time to peak strain.