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Table 1 The effects of intermediate dose dobutamine compared to exercise stress on left ventricular haemodynamics and strain parameters.

From: Myocardial haemodynamic responses to dobutamine stress compared to physiological exercise during cardiac magnetic resonance imaging

Parameter

Stressor

Significance

 

Rest 1

Rest 2

Exercise

Dobutamine

Rest 1 vs rest 2

Rest vs exercise

Rest vs dobutamine

Exercise vs dobutamine

Heart Rate (bpm)

70.2±13.7

68.6±11.9

108±10

116±11

NS

<0.05

<0.05

NS

Mean BP (mmHg)

89.4±6.4

91.5±10.2

124±19

103±11

NS

<0.05

<0.05

<0.05

CI (l/min/m2)

2.7±0.6

3.0±0.6

4.5±1.1

5.7±0.8

NS

<0.05

<0.05

<0.05

EDV (ml/m2)

73.2±15.9

76.9±12.5

72.0±17.2

64.5±11.5

NS

NS

<0.05

<0.05

ESV (ml/m2)

34.5±9.7

33.4±7.5

25.9±9.4

15.2±5.0

NS

<0.05

<0.05

<0.05

SV (ml/m2)

38.6±7.7

43.5±6.5

46.1±8.5

49.3±8.0

NS

<0.05

<0.05

NS

EF (%)

53.3±6.3

56.9±4.4

65.0±5.7

76.9±4.6

NS

<0.05

<0.05

<0.05

Err (%)

21.3±9.7

19.6±9.2

33.0±16.1

42.3±18.5

NS

NS

<0.05

NS

Err.tps (ms)

294±62

345±90

267±52

187±34

NS

<0.05

<0.05

<0.05

Ecc (%)

22.6±2.9

24.1±2.5

30.6±2.9

39.2±8.3

NS

<0.05

<0.05

<0.05

Ecc.tps (ms)

305±64

338±57

288±63

179±20

NS

<0.05

<0.05

<0.05

  1. Rest 1= rest prior to exercise study; Rest 2=rest prior to dobutamine study. Left ventricular volumes are indexed for body surface area and results are expressed as mean ± standard deviation. Paired t-test was used to test significance, set at a level of <0.05. CI= cardiac index, EDV=end diastolic volume, ESV=end systolic volume, SV=stroke volume, EF=ejection fraction, Err=short axis radial strain, Err.tps=radial time to peak strain, Ecc=circumferential strain, Ecc.tps=circumferential time to peak strain.
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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