|  | Quantitative results | Subjective 4D Flow Impact Factor (scale: changed clinical impression = 4, quantitative information added = 3, relevant but did not impact case = 2, information not relevant to case = 1) | |||||
---|---|---|---|---|---|---|---|---|
 |  | Clinical indication for 4D flow request | Quantitative comparison requested | 4D results | 2D PC results | Difference (%) | 4D flow alone (excludes 2D PC data) | Case including both 2D PC and 4D flow |
 | 1 | Biscuspid aortic valve, flow pattern interest | Regurgitant fraction | 16.57% | 25% | 34% | 3 | 2 |
 | 2 | Qp:Qs ratio in patient with VSD | Qsp:Qs ratio | 1.22 | Not measured | N/A | 3 | 3 |
 | 3 | Aortic stenosis, flow pattern interest | Aortic root peak velocity | 3.52 m/s | 3.8 m/s | 7% | 2 | 3 |
 | 4 | Biscuspid valve, flow pattern interest | Aortic root peak velocity | 2.35 m/s | Note measured | N/A | 3 | 2 |
Valvular | 5 | Biscuspid valve, flow pattern interest, aortic regurgitation. Regurgitant jet is very eccentric, limiting 2D assessment | Regurgitant fraction | 13.36% | 57% | 77% | 2 | 3 |
 | 6 | Biscuspid aortic valve, flow pattern interest, aortic regurgitation and stenosis assessment | Regurgitant fraction | 8.75% | 34% | 74% | 2 | 3 |
 | 7 | Aortic root velocity, 2D PC data underestimated velocity | Aortic root peak velocity | 4.08 m/s | 3.5 m/s | 17% | 4 | 4 |
 | 8 | Bicuspid aortic valve, flow pattern interest, aortic regurgitation and stenosis assessment | Regurgitant fraction | 4.66% | 15% | 69% | 3 | 2 |
Aneurysm | 9 | Flow pattern interest, aortic dilation | Ascending aorta peak velocity | 1.44 m/s | 1.3 m/s | 11% | 3 | 2 |
 | 10 | Aortic stenosis and regurgitation assessment | Regurgitant fraction | 38% | 55% | 31% | 3 | 3 |
 |  |  | Aortic root peak velocity | 3.36 m/s | 3.8 m/s | 12% |  |  |
 | 11 | Aortic stenosis and regurgitation assessment | Aortic root peak velocity | 3.89 m/s | 4.0 m/s | 5% | 4 | 4 |
 | 12 | Flow pattern interest, split flow right-left PA | Peak velocity through pulmonary anastomis | 2.32 m/s | 1.4 m/s | 66% | 4 | 4 |
 |  |  | Peak velocity through pulmonary post-stenosis | 2.70 m/s | 2.5 m/s | 8% |  |  |
Post-surgical | 13 | Aortic valve assessment | Ascending aorta peak velocity | Could not measure velocity secondary to aliasing artifact | Not measured | N/A | Not available | Not available |
 | 14 | Aortic stenosis and regurgitation assessment | Regurgitant fraction | 4.53% | Data limited by artifact | N/A | 3 | 3 |
 |  |  | Aortic root peak velocity | 3.11 m/s | Data limited by artifact | N/A |  |  |
Congenital | 15 | Large pulmonary regurgitant fraction by 2D PC | Pulmonary valve regurgitant fraction | 6.41% | 21.5% | 70% | 1 | 2 |
 | 16 | Flow pattern, Qp:Qs | Qp:Qs Ratio | 1.08 | 1 | 8% | 3 | 3 |
 | Average | 35% | 2.93 | 2.80 | ||||
 | St dev | 28.31% | 0.77 | 0.75 |