Voxel-wise quantification of myocardial blood flow with cardiovascular magnetic resonance: effect of variations in methodology and validation with positron emission tomography

Table 4 Comparison of CMR and PET-derived myocardial blood flow and myocardial reserve index

A. Mean values
	PET	Fermi	Tikhonov	TSVD
Overall MBF (mL/min/g)	1.23 ± 0.72	0.90 ± 0.44	1.05 ± 0.51	0.94 ± 0.47
Stress MBF (mL/min/g)	1.62 ± 0.81	1.16 ± 0.47	1.29 ± 0.51	1.21 ± 0.50
Rest MBF (mL/min/g)	0.84 ± 0.27	0.64 ± 0.20	0.80 ± 0.35	0.67 ± 0.17
MPR	1.97 ± 0.87	1.97 ± 1.13	1.73 ± 0.73	1.87 ± 0.79
B. Mean differences and limits of agreement
	Mean difference	p-value	95% limits of agreement
Overall MBF (mL/min/g)
PET – Fermi	0.35	<0.001	−0.56 to 1.26
PET – Tikhonov	0.19	0.014	−0.90 to 1.29
PET – TSVD	0.30	<0.001	−0.73 to 1.32
Stress MBF (mL/min/g)
PET – Fermi	0.48	<0.001	−0.65 to 1.61
PET – Tikhonov	0.34	0.004	−0.95 to 1.63
PET – TSVD	0.43	0.001	−0.89 to 1.75
Rest MBF (mL/min/g)
PET – Fermi	0.22	<0.001	−0.28 to 0.72
PET – Tikhonov	0.05	0.531	−0.72 to 0.82
PET – TSVD	0.17	<0.001	−0.32 to 0.66
MPR
PET – Fermi	0.02	0.869	−1.41 to 1.38
PET – Tikhonov	0.25	0.028	−0.99 to 1.50
PET – TSVD	0.14	0.200	−1.06 to 1.34

95% limits of agreement represent mean difference ± 2 standard deviations. Other abbreviations as per previous Tables.

ISSN: 1532-429X