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Table 1 Baseline patient characteristics

From: Cardiovascular magnetic resonance risk stratification in patients with clinically suspected myocarditis

All patients with follow-up

405 (92.5)

Time to follow-up [days]

1591 (1490–1739)

Gender, female

177 (43.7)

Age [years]

47.9 (36.9-60.8)

Referring physician

 

Inpatients

222 (54.8)

Outpatients referred by cardiologists

154 (38.0)

Outpatients referred by general practitioners

29 (7.2)

Primary cardiac symptoms leading to CMR (multiple possible)

 

Reduced LVEF

82 (20.2)

Pericardial effusion

6 (1.5)

ECG abnormality

131 (32.3)

Palpitations

92 (22.7)

Dyspnea

137 (33.8)

Angina/Chest pain

217 (53.6)

Abnormal fatigue

96 (23.8)

Wall motion abnormality

17 (4.2)

Ventricular arrythmias/Extrasystoles

45 (11.1)

Aborted SCD

6 (1.5)

Viral prodrome/history of infectious symptoms

130 (32.1)

Atrial fibrillation

50 (12.4)

Elevated troponin

38 (9.4)

Coronary angiography performed

205 (50.6)

EMB performed

78 (20.5)

Histopathological myocarditis in EMB

53 (68.8)

PVB19

29 (37.7)

HHV6

12 (15.6)

Double infection PVB19/HHV6

10 (13.0)

EBV

1 (1.3)

CMR imaging parameters

 

LVEF [%]

62.5 (55.0-68.0)

LV-EDV [ml]

137 (110–164)

LV-ESV [ml]

50 (36–72)

LVEDD [mm]

50 (46.0-54.5)

Pericardial effusion present

76 (18.8)

LGE present

114 (28.3)

Final diagnosis based on CMR

 

No cardiac pathology

225 (55.6)

Myocarditis

116 (28.8)

Other cardiac pathology

63 (15.6)

  1. Values shown are n (%) or medians and IQR = interquartile range (25th-75th percentiles) CMR, cardiovascular magnetic resonance; LVEF, left ventricular ejection fraction; SCD, sudden cardiac death, EMB, endomyocardial biopsy, PVB19, parvovirus B 19; HHV6, human herpes virus 6; EBV, ebstein-barr virus; CMR, cardiovascular magnetic resonance; EDV, enddiastolic volume; ESV, endsystolic volume; LVEDD, left ventricular enddiastolic diameter; LGE, late gadolinium enhancement.