Figure 9

Influence of heart rate on estimate of myocardial T1 for various MOLLI protocols with T2 = 45 ms, and flip angle = 35°. The original MOLLI protocol (top left) had a significant sensitivity to heart rate which may be reduced by increasing the time between inversions as in 5s(3s)3s protocol (top right), or by discarding samples for longer T1 as done in a ShMOLLI conditional reconstruction, approximated by 5(0) sampling for longer T1-values (bottom left). For lower values of T1 associated with Gd contrast, it is possible to improve accuracy using a 4s(1s)3s(1s)2s sampling scheme without incurring significant heart rate dependence (bottom right).