Cardiovascular outcome associations among cardiovascular magnetic resonance measures of arterial stiffness: the Dallas heart study

Table 2 Linear regression associations between traditional risk factors and CMR measures of arterial stiffness

Variable	Ascending aortic distensibility ΔmmHg × 10⁻³				Arch pulse wave velocity Δlog(m/s)				Total arterial compliance Δml/mmHg
	Univariate		Multivariate*		Univariate		Multivariate*		Univariate		Multivariate*
	β	P	β	P	β	P	β	P	β	P	β	P
Age (per 10 year increase)	−1.9	<.0001	−1.5	<.0001	0.25	<.0001	0.20	<.0001	−0.20	<.0001	−0.13	<.0001
Gender (male)	−1.0	<.0001	−0.83	<.0001	0.04	0.01	0.02	0.25	0.12	<.0001	0.003	0.89
Ethnicity (African American)	−0.82	<.0001	−0.04	0.68	0.16	<.0001	0.06	<.0001	−0.14
SBP (per 10 mmHg increase)	−0.98	<.0001	−0.56	<.0001	0.11	<.0001	0.07	<.0001	−0.14	<.0001	−0.11	<.0001
Use of hypertension medications	−2.3	<.0001	−0.25	0.20	0.28	<.0001	0.03	0.13	−0.31	<.0001	−0.01	0.72
Resting heart rate (per 10 beat per minute increase)	−0.39	<.0001	−0.38	<.0001	0.018	0.01	0.027	<.0001	−0.06	<.0001	−0.05	<.0001
Current smoking	−0.19	0.17	0.002	0.98	0.06	0.0008	0.02	0.37	0.005	0.87	−0.001	0.94
Diabetes mellitus	−2.2	<.0001	−0.32	0.04	0.18	<.0001	−0.01	0.60	−0.41	<.0001	−0.11	0.0002
Total cholesterol (per 10 mg/dL increase)	−0.12	<.0001	−0.11	0.28	0.014	<.0001	0.001	0.66	−0.014	<.0001	−0.005	0.03
HDL-C (per 10 mg/dL increase)	0.08	0.04	−0.10	0.76	0.02	0.0005	0.016	0.003	0.006	0.50	0.016	0.009
BMI (per 1 kg/m² increase)	−0.06	<.0001	−0.01	0.16	0.0005 =	0.96	−0.005	0.0004	−0.00	0.12	0.013	<.0001

β=beta coefficient for linear regression.
P=statistical significance.
*Multivariate analyses are adjusted for all covariates listed in the first column.

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