Figure 2
Post-mortem histopathology with correlating MR images in three patients with other cardiac causes of death. (A and B) Patient 1 with HCM: Interventricular septum showing myocyte disarray and hypertrophy. H&E stain, 10x objective. 4-chamber b-FFE MR image demonstrating severe basal septal hypertrophy and normal lateral wall thickness. (C and D) Patient 3 with acute myocardial infarction. Left anterior descending coronary artery atherosclerosis with acute occlusive thrombus. Movat pentachrome stain, 2x objective. 4-chamber T2 STIR MR image demonstrating regional hyperintense signal in the distal lateral wall, consistent with acute myocardial infarction/oedema. (E and F) Patient 13 with myocarditis. Myocardium showing extensive lymphohistiocytic infiltrate with associated myocyte necrosis. H&E stain, 10x objective. Short axis T2 STIR MR image demonstrating diffuse hyperintense signal in the basal infero-septal wall, consistent with myocarditis/myocardial oedema.