Figure 3
Post-mortem pathology with correlating MR image in two patients with death secondary to neurological pathology. (A and B) Patient 4 with Alagille syndrome. Liver showing a relative paucity of bile ducts in portal tract, typical of Alagille syndrome (arteriohepatic dysplasia). H&E stain, 40x objective. Coronal T1 inversion recovery brain MR image demonstrating unusual grey matter signal in temporal lobe white matter, suggesting grey matter heterotopia (C and D) Patient 17 with primary brain tumour. Thalamic glioblastoma multiforme, Grade IV, with intratumoral haemorrhage. Sagittal T2 weighted MR Image showing large well-circumscribed mass lesion in right thalamus with associated haemorrhage consistent with vascular tumour