| Severe AS (n = 22) | Normal controls (n = 15) | P value |
---|---|---|---|
Age (years) | 67 ± 9 | 63 ± 4 | 0.09 |
Male, n (%) | 15 (68) | 8 (53) | 0.34 |
Body mass index (kg/m2) | 27 ± 4 | 26 ± 3 | 0.38 |
BOLD signal intensity change (%) | 4.8 ± 9.6 | 18.2 ± 11.6 | 0.001 |
Myocardial perfusion reserve index | 1.0 ± 0.3 | 1.7 ± 0.3 | < 0.001 |
Left ventricular ejection fraction (%) | 74 ± 6 | 69 ± 4 | 0.01 |
Left ventricular end-diastolic volume (ml) | 148 ± 46 | 142 ± 32 | 0.65 |
Left ventricular end-systolic volume (ml) | 40 ± 20 | 44 ± 12 | 0.43 |
Left ventricular wall thickness (mm) | 17 ± 3 | 10 ± 1 | < 0.001 |
Left ventricular mass index (g/m2) | 99 ± 38 | 56 ± 13 | < 0.001 |
Aortic valve area (cm2) | 0.84 ± 0.10 | - | - |
LGE present, n (%) | 16 (73) | 0 (0) | - |
LGE volume when positive (%) | 17.6 ± 13.8 | - | - |