Mean ± SEM %-change of values from the baseline level at normoxia and normocapnia to levels with paCO
= 30 mmHg (black) and paCO
= 50 mmHg (green) (#p < 0.05 vs. baseline, *p < 0.05 difference between paCO
of 30 and 50). Oxygenation-sensitive signal intensity (OS-SI) of the three SAX slices (n = 8), the blood flow in the LAD (n = 8), and the oxygen extraction ratio (O2er, n = 7).